|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 22 and 239 of Human Smac|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29639 targets Smac in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29639 immunogen is recombinant fragment corresponding to a region within amino acids 22 and 239 of Human Smac.
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 0610041G12Rik; DFNA64; diablo homolog; Diablo homolog, mitochondrial; diablo, IAP-binding mitochondrial protein; diablo-like protein; DIABLO-S; Direct IAP-binding protein with low pI; mitochondrial; mitochondrial Smac protein; Second mitochondria-derived activator of caspase; SMAC; SMAC3
Gene Aliases: DFNA64; DIABLO; SMAC
UniProt ID: (Human) Q9HAV6
Entrez Gene ID: (Human) 56616
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