|Western Blot (WB)||1:500|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide SNADQRPHDSHSFQAKGC, corresponding to amino acids 80-96 of Human SmarcAL1.|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.02M potassium phosphate, pH 7.2, with 0.15M NaCl|
|Contains||0.01% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA1-31918 detects SmarcAL1 from human samples.
PA1-31918 has been successfully used in Western blot applications.
The PA1-31918 immunogen is: Synthetic peptide: SNADQRPHDSHSFQAKGC, corresponding to amino acids 80-96 of Human SmarcAL1.
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-driven annealing helicase; HARP; HepA-related protein; HHARP; SMARCA-like protein 1; Sucrose nonfermenting protein 2-like 1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
Gene Aliases: HARP; HHARP; SMARCAL1
UniProt ID: (Human) Q9NZC9
Entrez Gene ID: (Human) 50485
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