|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Immunomicroscopy (IM)||Assay Dependent|
|Western Blot (WB)||0.5-1.0 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||See 1 publications below|
|Immunoprecipitation (IP)||See 6 publications below|
|Immunocytochemistry (ICC)||See 5 publications below|
|Immunohistochemistry (IHC)||See 3 publications below|
|Tested Species reactivity||Fruit fly, Human, Pig, Rabbit, Rat|
|Published species reactivity||Dog , Rat , Fruit fly , Hamster , Mouse Human|
|Host / Isotype||Mouse / IgG3, kappa|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30% of patients with SLE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B polypeptide of Sm protein; sm protein B; Sm protein B/B'; sm-B; Sm-B/B'; sm-B/Sm-B'; SM11; small nuclear ribonucleoprotein polypeptide B; small nuclear ribonucleoprotein polypeptides B and B'; small nuclear ribonucleoprotein-associated protein B; Small nuclear ribonucleoprotein-associated proteins B and B'; smB; snRNP-B
Gene Aliases: CCMS; COD; Sm-B/B'; SmB/B'; SmB/SmB'; snRNP-B; SNRPB; SNRPB1
UniProt ID: (Human) P14678
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