|Immunoprecipitation (IP)||5-15 µg/mg lysate|
|Western Blot (WB)||1:2000-1:10,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||The epitope recognized by this antibody maps to a region between residue 334-384 of human sphingosine kinase 1 using the numbering given in entry NP_001136073.1|
|Purification||Antigen affinity chromatography|
|Storage buffer||tris citrate, pH 7-8|
|Contains||0.09% sodium azide|
|Storage conditions||4° C, do not freeze|
Sphingosine kinase 1 (SPHK1) catalyzes the phosphorylation of sphingosine to yield sphingosine-1-phosphate (SPP). SPP functions as a lipid signaling molecule that mediates both intra- and extra-cellular responses. SPHK1 activity may play a role in several cellular processes such as apoptisis, proliferation, inflammation, and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: SK 1; Sphingosine kinase 1; SPHK; SPK 1
Gene Aliases: SPHK; SPHK1; SPK
UniProt ID: (Human) Q9NYA1
Entrez Gene ID: (Human) 8877
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