|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||peptide with sequence C-KYLQQNRHVKDKN from the internal region of the SYK sequence|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
Predicted to react with dog, mouse and rat based on sequence homology.
In Western blot, this antibody detects a band at ~70 kDa in human bone marrow, lymph node and spleen lysates.
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp313N1010; FLJ25043; FLJ37489; p72-Syk; Spleen tyrosine kinase; Tyrosine-protein kinase SYK
Gene Aliases: p72-Syk; SYK
UniProt ID: (Human) P43405
Entrez Gene ID: (Human) 6850
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