|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence DEDEIHPLLIRDR-C, from the N-terminus of SYNGAP1 (aa60-72)|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
This antibody is predicted to react with human, rat, dog, pig and cow based on sequence homology.
The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp761G1421; KIAA1938; MRD5; Neuronal RasGAP; ras GTPase-activating protein SynGAP; Ras/Rap GTPase-activating protein SynGAP; RASA1; RASA5; synaptic Ras GTPase activating protein 1; synaptic Ras GTPase activating protein 1 homolog; Synaptic Ras GTPase-activating protein 1; Synaptic Ras-GAP 1; SYNGAP1
Gene Aliases: Gm1963; Syngap; Syngap1
UniProt ID: (Mouse) F6SEU4
Entrez Gene ID: (Mouse) 240057
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