|Flow Cytometry (Flow)||Assay Dependent|
|Tested Species reactivity||Human, Mouse, Pig, Rat|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17617 targets Syntaxin-1A in FACS applications and shows reactivity with Human, Mouse, Porcine, and Rat samples.
The MA5-17617 immunogen is human Syntaxin.
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Neuron-specific antigen HPC-1; P35A; STX1; STX1A; STXA1; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A (brain); syntaxin 1A (brain)-like; Syntaxin-1A
Gene Aliases: HPC-1; P35-1; Sap; STX1; STX1A; SYN1A
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