|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 777 and 841 of Human T1R1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28771 targets T1R1 in WB applications and shows reactivity with Human samples.
The PA5-28771 immunogen is synthetic peptide corresponding to a region within amino acids 777 and 841 of Human T1R1.
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor 70; G-protein coupled receptor 70; GPR70; seven transmembrane helix receptor; T1R1; Taste receptor type 1 member 1; taste receptor, type 1, member 1; TR1
Gene Aliases: GM148; GPR70; T1R1; TAS1R1; TR1
UniProt ID: (Human) Q7RTX1
Entrez Gene ID: (Human) 80835
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