|ELISA (ELISA)||5-10 µg/mL|
|Inhibition Assays (IA)||Assay Dependent.|
|Western Blot (WB)||5 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Purification||Ion-exchange chromatography, Ammonium sulfate precipitation|
|Storage buffer||50% water with 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-43024 detects TAFI in human samples.
MA1-43024 has successfully been used in WB, ELISA, IA applications.
MA1-43024 was derived from human TAFI and activated TAFI.
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The TAFI protein is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: carboxypeptidase B-like protein; Carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase R; Carboxypeptidase U; CPB2; CPU; PCPB; Plasma carboxypeptidase B; TAFI; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Gene Aliases: CPB2; CPU; PCPB; TAFI
UniProt ID: (Human) Q96IY4
Entrez Gene ID: (Human) 1361
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.