|Immunocytochemistry (ICC)||5 µg/ml|
|Immunofluorescence (IF)||5 µg/ml|
|Immunohistochemistry (Frozen) (IHC (F))||Assay-Dependent|
|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Human TARDBP.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
PA5-19712 targets TARDBP in IF, IHC (F), IP, and WB applications and shows reactivity with Human and mouse samples.
The PA5-19712 immunogen is synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Human TARDBP.
PA5-19712 detects TARDBP which has a predicted molecular weight of approximately 47 kDa.
HIV-1, the causative agent of acquired immunodeficiency syndrome located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Protein Aliases: RP4-635E18.2, ALS10, TDP-43, TAR DNA-binding protein 43; TAR DNA-binding protein 43; TAR DNA-binding protein-43; TDP-43
Gene Aliases: 1190002A23Rik; ALS10; C85084; TARDBP; TDP-43; TDP43