|Western Blot (WB)||0.5-1 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide SGYEKHFLPTPEELG, corresponding to amino acids 611-625 of Human TCCR.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-30730 detects TCCR from human samples.
PA1-30730 has been successfully used in Western blot applications.
The PA1-30730 immunogen is: Synthetic peptide: SGYEKHFLPTPEELG, corresponding to amino acids 611-625 of Human TCCR.
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: class I cytokine receptor; Cytokine receptor WSX-1; Cytokine receptor-like 1; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL27R; interleukin 27 receptor, alpha; Interleukin-27 receptor subunit alpha; T-cell cytokine receptor type 1; TCCR; Type I T-cell cytokine receptor; WSX1; ZcytoR1
Gene Aliases: CRL1; IL-27RA; IL27R; IL27RA; TCCR; UNQ296/PRO336; WSX1; zcytor1
UniProt ID: (Human) Q6UWB1
Entrez Gene ID: (Human) 9466
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