|Western Blot (WB)||0.1-0.3 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (QAYDRQKNPSKEER) corresponding to the internal amino acids of HNF1B|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine, mouse, porcine, rat and zebrafish based on sequence homology.
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FJHN; Hepatocyte nuclear factor 1-beta; HNF-1-beta; HNF1 beta A; HNF1B; HNF1beta; HNF2; Homeoprotein LFB3; LFB3; MODY5; TCF-2; TCF2; Transcription factor 2; transcription factor 2, hepatic; transcription factor 2, hepatic LF-B3 variant hepatic nuclear factor; Variant hepatic nuclear factor 1; VHNF1
Gene Aliases: FJHN; HNF-1-beta; HNF-1B; HNF1B; HNF1beta; HNF2; HPC11; LF-B3; LFB3; MODY5; TCF-2; TCF2; VHNF1
UniProt ID: (Human) P35680
Entrez Gene ID: (Human) 6928
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