|Immunofluorescence (IF)||20 ug/mL|
|Immunohistochemistry (IHC)||20 ug/ml|
|Western Blot (WB)||1 ug/mL|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 19 amino acid synthetic peptide near the amino terminus of human TCTEX1D4|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is mouse liver tissue lysate.
PA5-34447 can be used with blocking peptide PEP-1489.
Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: N22.1; novel Tctex-1 family domain-containing protein; Protein N22.1; t-complex-associated-testis-expressed 4; Tctex-2-beta; TCTEX1 domain containing 4; Tctex1 domain-containing protein 4; TCTEX1D4; Tctex2 beta
Gene Aliases: 4833401D15Rik; N22.1; TCTEX1D4
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