|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 191 of Human TEL|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28286 targets TEL in WB applications and shows reactivity with Human samples.
The PA5-28286 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 191 of Human TEL.
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ETS translocation variant 6; ets variant gene 6 (TEL oncogene); ETS-related protein Tel1; TEL; TEL/ABL; TEL1 oncogene; Transcription factor ETV6
Gene Aliases: ETV6; TEL; TEL/ABL; TEL1; THC5
UniProt ID: (Human) Q9UMF7
Entrez Gene ID: (Human) 2120
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