|Western Blot (WB)||0.2-8 µg/ml|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide region of human TFAM.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 2% sucrose|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-24435 detects TFAM in Human samples.
PA1-24435 has been successfully used in Western Blot procedures. By Western blot, PA1-24435 detects the ~ 29 kDa TFAM protein.
PA1-24435 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human TFAM.
TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Mitochondrial transcription factor 1; mitochondrial transcription factor A; MtTF1; mtTFA; TCF-6; TCF6; TCF6L1; TCF6L2; TCF6L3; Transcription factor 6; transcription factor 6-like 1; Transcription factor 6-like 2; transcription factor 6-like 2 (mitochondrial transcription factor); transcription factor 6-like 3; Transcription factor A, mitochondrial
Gene Aliases: MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3; TFAM
UniProt ID: (Human) Q00059
Entrez Gene ID: (Human) 7019
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