|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ELKRRKSKNEEKE) corresponding to the C-terminus amino acids of TFB1M|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine based on sequence homology.
The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CGI-75; CGI75; Dimethyladenosine transferase 1, mitochondrial; h-mtTFB; h-mtTFB1; homolog of yeast mitochondrial transcription factor B; hTFB1M; Mitochondrial 12S rRNA dimethylase 1; mitochondrial dimethyladenosine transferase 1; Mitochondrial transcription factor B1; mtTFB; OTTHUMP00000017473; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1; TFB1M; transcription factor B1, mitochondrial
Gene Aliases: CGI-75; CGI75; mtTFB; mtTFB1; TFB1M
UniProt ID: (Human) Q8WVM0
Entrez Gene ID: (Human) 51106
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