|ELISA (ELISA)||1 µg/ml|
|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Full length human TGF beta-1 (Met1-Ser390) fused with c-terminal polyhistidine tag|
MA1-169 has been successfully used as a coating antibody in a sandwich ELISA with Product # MA1-116 used as a detection antibody.
TGF beta-1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines found almost ubiquitously in tissues. Transforming growth factor (TGF-b) is stored in the extracellular matrix as a latent complex with its prodomain. Activation of TGF-b1 requires the binding of aV integrin to an RGD sequence in the prodomain and exertion of force on this domain, which is held in the extracellular matrix by latent TGF-b binding proteins. Latent forms are complexes of TGF-beta, an aminoterminal portion of the TGF-beta precursor, designated TGF-LAP (TGF-latency associated peptide), and a specific binding protein known as LTBP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DPD1; Latency-Associated Peptide; prepro-transforming growth factor beta-1; TGF beta; TGF beta-1; TGF beta-1 protein; TGF-B1; TGF-beta-1; TGFB; Transforming Growth Factor beta-1
Gene Aliases: CED; DPD1; LAP; TGFB; TGFB1; TGFbeta
UniProt ID: (Human) P01137
Entrez Gene ID: (Human) 7040
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