|Immunohistochemistry (Paraffin) (IHC (P))||1:300|
|Western Blot (WB)||1:10,000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Partial recombinant human THAP11 protein expressed in E. coli.|
|Storage buffer||whole serum|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The target sequence has 94% sequence homology with rat and 95% sequence homology with bovine.
THAP11 is a member of the thanatos-associated proteins (THAP) family, which are zinc-dependent, sequence-specific DNA-binding factors involved in cell proliferation, apoptosis, cell cycle, chromatin modification and transcriptional regulation (Zhu, et al). THAP11 has been hypothesized to be a cell growth inhibitor via the repression of c-myc (Zhu, et al), and THAP11 expression has also been linked to the proliferation of embryonic stem cells (Dejosez M et al).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CTG-B43a; CTG-B45d; HRIHFB2206; RONIN; THAP domain-containing protein 11
Gene Aliases: 2810036E22Rik; AB041579; CTG-B43a; CTG-B45d; HRIHFB2206; MNCb-2032; RONIN; THAP11
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