|Western Blot (WB)||0.25-0.5 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (40 CEMKVEEEHTNAIGTLHG 57) of THEM2 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
The THEM2 gene encodes an uncharacterized hypothalamus protein and is part of the thioesterase superfamily. The thioesterase superfamily catalyzes the hydrolysis of long-chain fatty acyl-CoA thioesters. THEM2 belongs to the hotdog-fold enzyme superfamily containing a hotdog-fold and forms a back-to-back tetramer as other hotdog proteins. The protein is highly expressed in the kidney, and moderately expressed in the liver, brain, large intestine, and small intestine. Human THEM2 is co-localized with, and binds to, microtubules in all stages of the cell cycle as confirmed by immunostaining and GFP-Tag experiments. The protein is essential for eukaryotic cells growth. The gene encoding for human THEM2 is localized in the chromosomal region 6p22.2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acyl-CoA thioesterase 13; Acyl-coenzyme A thioesterase 13; HT012; hypothalamus protein HT012; PNAS-27; THEM2; Thioesterase superfamily member 2
Gene Aliases: 0610006O17Rik; ACOT13; HT012; PNAS-27; THEM2
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