|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 79 and 300 of Human TIAL1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30191 targets TIAL1 in WB applications and shows reactivity with Human samples.
The PA5-30191 immunogen is recombinant fragment corresponding to a region within amino acids 79 and 300 of Human TIAL1.
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: aging-associated gene 7 protein; Nucleolysin TIAR; T-cluster binding protein; TCBP; TIA-1-related nucleolysin; TIA-1-related protein; TIAR
Gene Aliases: TCBP; TIAL1; TIAR
UniProt ID: (Human) Q01085
Entrez Gene ID: (Human) 7073
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