|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human TIEG2|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse based on sequence homology.
TIEG2 is a transcription factor. The protein activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. It represses transcription of SMAD7 which enhances TGF-beta signaling. It induces apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Krueppel-like factor 11; Kruppel-like factor 11; TGFB-inducible early growth response protein 2; TIEG-2; Transforming growth factor-beta-inducible early growth response protein 2
Gene Aliases: FKLF; FKLF1; KLF11; MODY7; TIEG2; Tieg3
UniProt ID: (Human) O14901
Entrez Gene ID: (Human) 8462
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