|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 123 and 186 of TLP|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28088 targets TLP in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-28088 immunogen is a synthetic peptide corresponding to a region within amino acids 123 and 186 of TLP.
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 21 kDa TBP-like protein; 21-kDA TBP-like protein; MGC:8389; MGC:9620; Second TBP of unique DNA protein; STUD; TATA box binding protein-like protein; TATA box-binding protein-like protein 1; TATA box-binding protein-related factor 2; TBP-like 1; TBP-like factor; TBP-like protein 1; TBP-related factor 2; TBP-related protein; TLF; TLP; TRF2
Gene Aliases: 4732475G08; AW011832; AW491032; D18347; MGC:8389; MGC:9620; STD; STUD; TBPL1; TLF; TLP; TLP21; TRF2; TRP
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