|Flow Cytometry (Flow)||1:50|
|Functional Assay (FN)||1:50|
|Immunohistochemistry (Frozen) (IHC (F))||1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50|
|Tested Species reactivity||Mouse|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Murine TLR2 peptide|
|Storage buffer||PBS with 0.1% BSA|
|Storage conditions||4° C|
MA1-40080 detects TLR2 from mouse samples.
MA1-40080 has been successfully used in flow cytometry, ELISA, function assays and immunohistochemistry (paraffin and frozen) applications.
The MA1-40080 immunogen is mouse TLR2.
The TLR2 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This protein is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD282; TIL4; Toll-like Receptor 2; toll/interleukin 1 receptor-like 4; toll/interleukin-1 receptor-like protein 4
Gene Aliases: Ly105; Tlr2
UniProt ID: (Mouse) Q9QUN7
Entrez Gene ID: (Mouse) 24088
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