|Flow Cytometry (Flow)||10 µl for 10^6 cells in 100 µl|
|Blocking Assay (BLOCK)||See 1 publications below|
|Tested Species reactivity||Human, Non-human primate|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Ba/F3 cell line expressing TLR4.|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-20236 detects TLR4 in human and non-human primate samples.
MA1-20236 has been successfully used in FACS procedures.
The MA1-20236 immunogen corresponds to Ba/F3 cell line expressing TLR4.
TLR4 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARMD10; CD284; homolog of Drosophila toll; hToll; TLR-4; TOLL; Toll-like Receptor 4
Gene Aliases: ARMD10; CD284; TLR-4; TLR4; TOLL
UniProt ID: (Human) O00206
Entrez Gene ID: (Human) 7099
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