|Flow Cytometry (Flow)||10 µl for 10^6 cells in 100 µl|
|Blocking Assay (BLOCK)||See 1 publications below|
|Tested Species reactivity||Guinea pig, Human, Pig|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Ba/F3 cell line expressing TLR4|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
MA1-22766 detects TLR4 (FITC) in Human, Pig and Guinea Pig samples.
MA1-22766 has been successfully used in FACS procedures.
MA1-22766 immunogen corresponds to Ba/F3 cell line expressing TLR4.
Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARMD10; CD284; homolog of Drosophila toll; hToll; TLR-4; TOLL; Toll-like Receptor 4
Gene Aliases: ARMD10; CD284; TLR-4; TLR4; TOLL
UniProt ID: (Human) O00206
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