|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 22-48 amino acids from the N-terminal region of human TNFRSF6B|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DCR3; Decoy receptor 3; decoy receptor 3 variant 1; decoy receptor 3 variant 2; Decoy receptor for Fas ligand; DJ583P15.1.1; M68; M68E; TR6; Tumor necrosis factor receptor superfamily member 6B; tumor necrosis factor receptor superfamily member 6b, decoy; tumor necrosis factor receptor superfamily, member 6b, decoy
Gene Aliases: DCR3; DJ583P15.1.1; M68; M68E; TNFRSF6B; TR6; UNQ186/PRO212
UniProt ID: (Human) O95407
Entrez Gene ID: (Human) 8771
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.