|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Immunoprecipitation (IP)||0.5 mg/ml|
|Immunoprecipitation (IP)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||1106-1325 of 1327 of TNKS1 Protein.|
|Contains||0.09% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 5; ARTD5; PARP-5a; PARP5A; PARPL; pART5; Poly [ADP-ribose] polymerase 5A; TANK1; tankyrase 1; Tankyrase I; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; Tankyrase-1; TIN1; TINF1; TNKS-1; TNKS1; TRF1-interacting ankyrin-related ADP-ribose polymerase; TRF1-interacting ankyrin-related ADP-ribose polymerase 1
Gene Aliases: 4930554K12Rik; AI662855; ARTD5; C86528; D130072O21Rik; mTNKS1; PARP-5a; PARP5A; PARPL; pART5; TANK1; TIN1; TINF1; TNKS; TNKS1
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