|Immunohistochemistry (Frozen) (IHC (F))||1:2000|
|Immunoprecipitation (IP)||Assay dependent|
|Western Blot (WB)||1:250|
|Miscellaneous PubMed (MISC)||See 2 publications below|
|Tested Species reactivity||Mouse, Rat|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues Y(499) D G P V F D L T T T P K(511) of TUC-4a (residues 612-624 of TUC-4b).|
|Storage buffer||whole serum|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA3-120 detects TOAD-64 in rat samples.
PA3-120 has been successfully used in Western blot, immunoprecipitation and immunohistochemistry (frozen) procedures. By Western blot, this antibody detects an 64 kDa protein representing TOAD-64 in rat samples.
The PA3-120 immunogen is a synthetic peptide corresponding to residues Y(499) D G P V F D L T T T P K(511) of TUC-4a (residues 612-624 of TUC-4b).
TOAD-64 is a 64 kDa intracellular neural protein, which belongs to a family of genes that inhibit nerve growth. It also appears to be involved in a role of axon outgrowth. Preliminary results indicate inhibition of TOAD-64 expression poteintiates neurite outgrowth, and may lead to the design of therapies that promote axonal regeneration. Antibodies to TOAD-64 render neurons insensitive to extracellular compounds that inhibit neuron growth. Very few reagents are able to identify newly born neurons as well as antibodies to TOAD-64.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collapsin response mediator protein 2; CRMP-2; Dihydropyrimidinase-related protein 2; DPYL2; DRP-2; DRP2; TOAD-64; Turned On After Division 64; Turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP-2; Unc-33-like phosphoprotein 2
Gene Aliases: AI851130; Crmp2; Dpysl2; DRP2; Musunc33; TOAD-64; Ulip2
Molecular Function: hydrolase
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