|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (TEPLPEKTQES) corresponding to the C-terminus amino acids of TPD52|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine based on sequence homology.
Principal Names: Tumor Protein D52; D52; hD52; N8L; N8 Protein; PC-1; PrLZ; Official Gene Symbol: TPD52 Gene ID: 7163 (Human) Gene Map Locus: 8q21 (Human) TPD52, a 28KDa protein, is a member of D52 protein family. Members of this family have been found to be involved in cell proliferation. TPD52 has a ubiquitous expression pattern and consists of a coiled-coil motif responsible for protein-protein interactions. Its expression is characteristically up-regulated during differentiation of B-cells to plasma cells. It binds to annexin VI in a Ca2+-dependent manner. Reports suggest TPD52 might be involved in Ca2+-dependent signaling, cell proliferation, vesicle trafficking and regulation of secretory processes in plasma cells. It is dysregulated in many cancer types suggesting a therapeutic intervention.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D52; hD52; N8L; PC-1; PC1/MRPS28 fusion protein; PrLZ; prostate and colon associated protein; prostate leucine zipper; Protein N8; TPD52; Tumor protein D52
Gene Aliases: D52; hD52; N8L; PC-1; PrLZ; TPD52
UniProt ID: (Human) P55327
Entrez Gene ID: (Human) 7163
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