|Flow Cytometry (Flow)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Flow Cytometry (Flow)||See 3 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant human TR2 protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-13986 targets TR2/HVEM in FACS, and IF applications and shows reactivity with Human samples.
The MA5-13986 immunogen is recombinant human TR2 protein.
TNF receptor like-2 (TR2) (also known as herpesvirus entry mediator (HVEM)) is expressed in multiple human tissues and cell lines and shows a constitutive and relatively high expression in peripheral T and B lymphocytes, and monocytes. It is a member of TNF receptor family. TR2/HVEM is a receptor for herpes virus. It also acts as a receptor for LIGHT (also known as HVEM ligand), a member of TNF family. TR2 protein inhibits a mixed lymphocyte reaction-mediated proliferation suggesting that the receptor and/or its ligand play a role in T cell stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD270; CD40-like protein; delta transmembrane LIGHT; Herpes virus entry mediator A; herpes virus entry mediator ligand; Herpesvirus entry mediator A; TNFRSF14; TR2; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; tumor necrosis factor superfamily member LIGHT
Gene Aliases: ATAR; CD270; HVEA; HVEM; LIGHTR; TNFRSF14; TR2; UNQ329/PRO509
UniProt ID: (Human) Q92956
Entrez Gene ID: (Human) 8764
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.