|Immunohistochemistry (Paraffin) (IHC (P))||5-10 µg/ml|
|Western Blot (WB)||5-8 µg/ml|
|Tested Species reactivity||Horse, Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (344 REAARGEAARRALQ 357) of TRBP protein.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
TRBP is an RNA associated nuclear protein. It contains 3 DRBM (double stranded RNA-binding) domains and plays an important role by binding to HIV-1 TAR RNA located in the long terminal repeat (LTR). TRBP acts synergistic with viral TAT protein in HIV-1 expression activation. It binds preferentially to TAR and other double-stranded RNAs with G+C-rich characteristics. It is important in regulation of transcription from RNA polymerase II promoter and is widely expressed in most of the tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LOQS; RISC-loading complex subunit TARBP2; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; TAR (HIV-1) RNA binding protein 2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TARBP2; trans-activation responsive RNA-binding protein; Trans-activation-responsive RNA-binding protein; TRBP; TRBP1; TRBP2
Gene Aliases: LOQS; TARBP2; TRBP; TRBP1; TRBP2
UniProt ID: (Human) Q15633
Entrez Gene ID: (Human) 6895
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