|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 716-745 amino acids from the C-terminal region of human TRIAD3 (UBCE7IP1)|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
UBCE7IP1 is a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E3 ubiquitin ligase; E3 ubiquitin-protein ligase RNF216; E3 ubiquitin-protein ligase TRIAD3; RING finger protein 216; RING-type E3 ubiquitin transferase RNF216; Triad domain-containing protein 3; UbcM4-interacting protein 83; Ubiquitin conjugating enzyme 7 interacting protein 1; Ubiquitin-conjugating enzyme 7-interacting protein 1; ZIN; Zinc finger protein inhibiting NF-kappa-B
Gene Aliases: 2810055G22Rik; AI647468; AU019462; C86502; CAHH; F830018F18Rik; RNF216; TRIAD3; U7I1; UBCE7IP1; UIP83; ZIN
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