|Immunohistochemistry (IHC)||1:300 - 1:2000|
|Western Blot (WB)||1:300 - 1:2000|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from the 4th cytoplasmic loop of mouse TRPC6 conjugated to an immunogenic carrier protein|
|Storage buffer||whole serum|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
The immunogenic sequence shares 94% identity with TRPC3 and TRPC7 sequences.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcium entry channel; member 6; mTrp3; receptor-activated cation channel TRP3; short transient receptor potential channel 3; Short transient receptor potential channel 6; Short transient receptor potential channel 7; subfamily C; transient receptor potential cation channel; transient receptor protein 3; Transient receptor protein 6; Transient receptor protein 7; TRP-3; TRP-6; TRP-7; trp-related protein 3; Trp6; TrpC6; TrpC7
Gene Aliases: AV025995; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Mwk; Trcp3; TRP-6; Trp3; Trp6; TRP7; Trpc6; Trpc7; Trrp3; Trrp6; Trrp8
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