|Immunohistochemistry (IHC)||10-50 µg/ml|
|Western Blot (WB)||10-50 µg/ml|
|Tested Species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide from the 4th cytoplasmic loop of rat TRPC4 conjugated to an immunogenic carrier protein|
|Purification||Ammonium sulfate precipitation|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Reconstitute with 500 ul of distilled water.
Centrifuge to remove any insoluble material.
Thought to form non-selective a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. Isoform alpha but not isoform beta associates with inositol-1,4,5-triphosphate receptor (ITPR). Interacts with NHERF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: capacitative calcium entry channel 1; CCE1; CCE1. GENE NAME: Trpc4; short transient receptor potential channel 4; transient receptor potential channel 4; transient receptor potential protein 4; Trp4
Gene Aliases: Trp4; Trrp4
Entrez Gene ID: (Rat) 84494
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