|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1075-1104 amino acids from the C-terminal region of human TRPM8|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with rat based on sequence homology.
TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.
Protein Aliases: Long transient receptor potential channel 6; LTrpC-6; LTrpC6; short form of the TRPM8 cationic channel; transient receptor melastatin 8 variant 1; transient receptor melastatin 8 variant 2; Transient receptor potential cation channel subfamily M member 8; transient receptor potential cation channel, subfamily M, member 8; Transient receptor potential p8; transient receptor potential subfamily M member 8; Transient receptor potential-p8; Trp-p8; TRPM8
Gene Aliases: LTRPC6; TRPM8; TRPP8
UniProt ID: (Human) Q7Z2W7
Entrez Gene ID: (Human) 79054