|Western Blot (WB)||1:300-1:2000|
|Tested Species reactivity||Rat|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from the 3d extracellular loop of rat TRPV2|
|Storage buffer||whole serum|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Reconstitute with 100 ul of distilled water.
Centrifuge to remove any insoluble material.
Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by growth factors, like IGF1, PDGF and morphogenetic neuropeptide/head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. Interacts with a cAMP-dependent protein kinase type II regulatory subunit (PRKAR2A or PRKAR2B) and ACBD3. Interacts with RGA. Ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal chord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Osm-9-like TRP channel 2; OTRPC2; S; Stretch-activated channel 2B; Transient receptor potential cation channel subfamily V member 2; TrpV2; Vanilloid receptor-like protein 1; VRL-1
Gene Aliases: Sac2b; Trpv2; Vrl1
UniProt ID: (Rat) Q9WUD2
Entrez Gene ID: (Rat) 29465
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