|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 1397-1426 amino acids from the central region of human TSC2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Mutations in this gene lead to tuberous sclerosis complex.Its gene product is believed to be a tumor suppressor and is ableto stimulate specific GTPases. The protein associates with hamartinin a cytosolic complex, possibly acting as a chaperone forhamartin. Alternative splicing results in multiple transcriptvariants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: protein phosphatase 1, regulatory subunit 160; TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein
Gene Aliases: LAM; PPP1R160; TSC2; TSC4
UniProt ID: (Human) P49815
Entrez Gene ID: (Human) 7249
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.