|Immunohistochemistry (Paraffin) (IHC (P))||7 - 12 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from C-terminus of human TSH Receptor.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Bat, Bovine, Cat, Panda, Pig (90%) Sheep, Dog, Horse, Rabbit (85%).
The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CHNG1; HTSHR-I; LGR3; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2; Thyroid-stimulating hormone receptor; Thyrotrophin receptor; Thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSH receptor; TSH-R; TSHR
Gene Aliases: CHNG1; hTSHR-I; LGR3; TSHR
UniProt ID: (Human) P16473
Entrez Gene ID: (Human) 7253
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