|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 83 and 335 of Human TXNL2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31160 targets TXNL2 in IF and WB applications and shows reactivity with Human and mouse samples.
The PA5-31160 immunogen is recombinant fragment corresponding to a region within amino acids 83 and 335 of Human TXNL2.
This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GLRX4; glutaredoxin 4; Glutaredoxin-3; GRX3; GRX4; PICOT; PKC interacting cousin of thioredoxin; PKC-interacting cousin of thioredoxin; PKC-theta-interacting protein; PKCq-interacting protein; testicular tissue protein Li 75; thioredoxin-like 2; Thioredoxin-like protein 2; TXNL2; TXNL3
Gene Aliases: GLRX3; GLRX4; GRX3; GRX4; HUSSY-22; PICOT; TXNL2; TXNL3
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