|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 480 and 662 of Human TYW1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30677 targets TYW1 in IF and WB applications and shows reactivity with Human samples.
The PA5-30677 immunogen is recombinant protein fragment corresponding to a region within amino acids 480 and 662 of Human TYW1.
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW1 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Radical S-adenosyl methionine and flavodoxin domain-containing protein 1; radical S-adenosyl methionine and flavodoxin domains 1; RSAFD1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase; tRNA wybutosine-synthesizing protein 1 homolog; tRNA-yW synthesizing protein 1 homolog A; tRNA-yW-synthesizing protein; TYW1A; YPL207W
Gene Aliases: RSAFD1; TYW1; TYW1A; YPL207W
UniProt ID: (Human) Q9NV66
Entrez Gene ID: (Human) 55253
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