|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 2 publications below|
|Tested Species reactivity||Bovine, Human, Non-human primate, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Purified bovine Tau|
|Storage conditions||4° C|
MN1010B targets Tau in ELISA and WB applications and shows reactivity with Bovine, Human, Non-human primate, and Rat samples.
The MN1010B immunogen is purified bovine Tau.
MN1010B detects Tau which has a predicted molecular weight of approximately 79 kDa.
Paired helical filament (PHF) is a major component of the neurofibrillary tangles involved in the pathology of Alzheimer and quote;s disease. PHFs are composed of the microtubule-associated protein tau in a hyper-phosphorylated state (ref1). Tau protein is produced by a single gene expressed predominantly in neurons. The Tau gene undergoes complex alternative splicing, yielding six different isoforms of tau in the adult brain. Following translation, the tau protein can be further modified by phosphorylation at several different sites
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein beta1/gamma2 subunit-interacting factor 1; microtubule associated protein tau; Microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; protein phosphatase 1, regulatory subunit 103; Tau microtubule-associated protein
Gene Aliases: BOS_19251; DDPAC; FTDP-17; MAPT; MAPTL; MSTD; Mtapt; MTBT1; MTBT2; PPND; PPP1R103; pTau; RNPTAU; TAU
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