|Flow Cytometry (Flow)||1:50-1:200|
|Immunohistochemistry (Frozen) (IHC (F))||1:50-1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgM|
|Immunogen||Full-length recombinant hTERT from insect cells.|
|Contains||0.1% sodium azide|
|Storage conditions||-20°C or -80°C if preferred|
Suggested positive control: 293T whole cell lysates, HeLa whole cell lysates, antigen standard for TERT (transient overexpression lysate).
Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase.
Telomerase (TERT) is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKCA2; DKCB4; EST2; HEST2; hTERT; hTRT; TCS1; Telomerase catalytic subunit; Telomerase reverse transcriptase; Telomerase-associated protein 2; TP2; TRT
Gene Aliases: CMM9; DKCA2; DKCB4; EST2; hEST2; hTRT; PFBMFT1; TCS1; TERT; TP2; TRT
UniProt ID: (Human) O14746
Entrez Gene ID: (Human) 7015
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.