|Immunohistochemistry (Paraffin) (IHC (P))||1:20-1:30|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant protein corresponding to the amino terminal region of the TdT molecule|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-11466 targets Terminal Deoxyribonucleotidyl Transferase in IHC (P) applications and shows reactivity with Human samples.
The MA5-11466 immunogen is recombinant protein corresponding to the amino terminal region of the TdT molecule.
Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyses the polymerization of deoxynucleotides at the 3' hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template. TdT is considered to be a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leuksemias. The determination of TdT expression is most valuable when it is different to differentiate histologically between lymphoblastic lymphoma and Burkitt's lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: deoxynucleotidyltransferase, terminal; DNA nucleotidylexotransferase; nucleosidetriphosphate:DNA deoxynucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; terminal deoxyribonucleotidyltransferase; Terminal transferase
Gene Aliases: DNTT; TDT
UniProt ID: (Human) P04053
Entrez Gene ID: (Human) 1791
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