|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Fusion protein of N-terminal peptide from mouse TR4.|
|Storage buffer||whole serum|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: NR2C2; Nuclear hormone receptor TR4; Nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; nuclear receptor subfamily 2, group H, member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; orphan receptor TR4; orphan receptor, TR4; TAK1; testicular nuclear receptor 4; Testicular receptor 4; TR4; TR4 orphan receptor; TR4-NS orphan receptor
Gene Aliases: mKIAA4145; Mtr2r1; NR2C2; TAK1; TR4
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