|Flow Cytometry (Flow)||1:2|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:50|
|Immunohistochemistry (IHC)||See 7 publications below|
|Immunocytochemistry (ICC)||See 2 publications below|
|Tested Species reactivity||Human, Rat|
|Published species reactivity||Rat , Human , Mouse|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant protein encoding the six repeated EGF domains of human thrombomodulin|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-11454 targets CD141 in IHC (P), FACS and ICC/IF applications and shows reactivity with Human and Rat samples.
The MA5-11454 immunogen is recombinant protein encoding the six repeated EGF domains of human thrombomodulin.
Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AHUS6; BDCA3; CD141; CD141 antigen; DC141; Fetomodulin; THBD; THPH12; THRM; thrombomdulin; Thrombomodulin; TM
Gene Aliases: AHUS6; BDCA3; CD141; THBD; THPH12; THRM; TM
UniProt ID: (Human) P07204
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.