|Immunohistochemistry (Paraffin) (IHC (P))||4 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human TBXA2R.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Dog, Panda (95%) Elephant (90%) Bat, Bovine, Pig (85%) Opossum (80%).
The thromboxane A2 receptor (TBXA2R) is a member of the Prostanoid Receptor subfamily. TBXA2R performs an essential role in hemostasis by interacting with thromboxane A2 to induce platelet aggregation. Thromboxane A2 has been implicated in myocardial infarct, stroke, and asthma. Additionally, thromboxane-prostanoid receptors have been implicated in the pathogenesis of cardiovascular diseases. Changes in TBXA2R function have also been linked to a hereditary bleeding disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BDPLT13; Prostanoid TP receptor; TBXA2R; Thromboxane A2 receptor; Txa2 receptor; TXA2-R
Gene Aliases: BDPLT13; TBXA2R; TXA2-R
UniProt ID: (Human) P21731
Entrez Gene ID: (Human) 6915
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