|Immunohistochemistry (Frozen) (IHC (F))||1:1000-1:3000|
|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Human, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide conjugated to KLH derived from within residues 850 - 950 of Human Tomosyn.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody is predicted to react with mouse, cow and human based on sequence homology.
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lethal(2) giant larvae protein homolog 3; putative protein product of Nbla04300; RP11-361F15.4, FLJ30922, LGL3, LLGL3, MGC141942, MGC141968, Nbla04300, lethal(2) giant larvae protein homolog 3; syntaxin binding protein 5 (tomosyn); Syntaxin-binding protein 5; tomosyn; Tomosyn-1
Gene Aliases: LGL3; LLGL3; Nbla04300; STXBP5
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