|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 208 of Human Tomosyn|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31205 targets Tomosyn in WB applications and shows reactivity with Human samples.
The PA5-31205 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 208 of Human Tomosyn.
Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lethal(2) giant larvae protein homolog 3; LGL3; LLGL3; Nbla04300; putative protein product of Nbla04300; syntaxin binding protein 5 (tomosyn); Syntaxin-binding protein 5; tomosyn; Tomosyn-1
Gene Aliases: LGL3; LLGL3; Nbla04300; STXBP5
UniProt ID: (Human) Q5T5C0
Entrez Gene ID: (Human) 134957
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