|Western Blot (WB)||1:300-1:2000|
|Tested Species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from c-terminal region of rat trace amine-associated receptor 4|
|Storage buffer||whole serum|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Reconstitute with 100 ul of distilled water.
Centrifuge to remove any insoluble material.
Orphan receptor. Could be a receptor for trace amines. Of the biogenic trace amine tested, activated only by beta-phenylethylamine (beta-PEA) and tryptamine; however, the response is of low potency. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. This receptor seems to be mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-phenylethylamine receptor; Gm226; mTaar4; Ta2; TAAR 4; TaR-2; TaR-4; trace amine associated receptor 4; Trace amine receptor 2; trace amine receptor 4; Trace amine-associated receptor 4; trace-amine-associated receptor 4
Gene Aliases: Gm226; Ta2; Taar4; taR-2; taR-4; Tar2; Trar2
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