|Western Blot (WB)||1:1000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phosphopeptide from the amino terminus of human tuberin|
|Storage buffer||0.01M HEPES, pH 7.5, with 50% glycerol, 0.15M NaCl, 100µg/ml BSA|
|Contains||<0.02% sodium azide|
It is not recommended to aliquot this antibody.
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: OTTHUMP00000198394; protein phosphatase 1, regulatory subunit 160; Tuberin; Tuberous sclerosis 2 protein
Gene Aliases: LAM; PPP1R160; TSC2; TSC4
UniProt ID: (Human) P49815
Entrez Gene ID: (Human) 7249
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